I have been reading a lot about the uptake and metabolism of silver inside the body lately, as there are many myths circulating about the subject, and also to think about alternative capping agents. I have been using ionic silver, uncapped and citrate capped nano silver topically with great success, and gelatin capped nano silver internally, as suggested by the forum.
However, I noticed that most research paper about "in vivo" (rats!) application of nano silver against bacteria, virus and cancers use citrate or PVP capped nano silver, and I found this interesting study from 2013 that shows that uncapped nano silver is rendered virtually useless (as bactericide) when in presence of blood or FBS, because of the high adhesion of proteins in the blood (e.g. albumin).
Citrate and PVP capped nano silver, on the other hand, show very little adhesion, and high bactericidal effect (ionic silver was not tested, nor gelatin capped nano silver).
What is missing in this study is the mouth -> stomach -> intestinal route, but I was wondering what this study would mean for ingestion of gelatin capped nano silver. In theory, the gut enzymes will strip the gelatin off the nano silver, making it basically uncapped nano silver, with particles small enough to pass from the gut to the blood stream. But would it, in that case not be rendered inert as the study shows?
https://aac.asm.org/content/57/10/4945